標(biāo)題: Titlebook: Anthracycline Chemistry and Biology II; Mode of Action, Clin Karsten Krohn Book 2008 Springer-Verlag Berlin Heidelberg 2008 biochemistry.bi [打印本頁(yè)] 作者: Radiofrequency 時(shí)間: 2025-3-21 17:08
書(shū)目名稱Anthracycline Chemistry and Biology II影響因子(影響力)
書(shū)目名稱Anthracycline Chemistry and Biology II影響因子(影響力)學(xué)科排名
書(shū)目名稱Anthracycline Chemistry and Biology II網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Anthracycline Chemistry and Biology II網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Anthracycline Chemistry and Biology II被引頻次
書(shū)目名稱Anthracycline Chemistry and Biology II被引頻次學(xué)科排名
書(shū)目名稱Anthracycline Chemistry and Biology II年度引用
書(shū)目名稱Anthracycline Chemistry and Biology II年度引用學(xué)科排名
書(shū)目名稱Anthracycline Chemistry and Biology II讀者反饋
書(shū)目名稱Anthracycline Chemistry and Biology II讀者反饋學(xué)科排名
作者: 笨拙處理 時(shí)間: 2025-3-21 21:44 作者: jumble 時(shí)間: 2025-3-22 04:16
Einführung in die Analyse von Prosatexten of fusion protein.Among the novelty in ADEPT approaches, one of the most relevant was based on the design of multiplespacer systems..Closely related to ADEPT, new approaches to selectively deliver prodrug-releasing enzymes intumor cells have been still studied or proposed by means of gene (GDEPT), 作者: Gentry 時(shí)間: 2025-3-22 06:44
https://doi.org/10.1007/978-3-476-98966-6ehyde in vivo remains a?mystery. In vitro, doxorubicin reacts withformaldehyde to give firstly a?monomeric oxazolidine, doxazolidine, and secondly a?dimeric oxazolidine,doxoform. Doxorubicin reacts with formaldehyde in the presence of salicylamide to give the N-Mannich baseconjugate, doxsaliform. Do作者: 寒冷 時(shí)間: 2025-3-22 10:17 作者: harangue 時(shí)間: 2025-3-22 13:15 作者: 下級(jí) 時(shí)間: 2025-3-22 17:59
Doxorubicin Conjugates for Selective Delivery to Tumors, of fusion protein.Among the novelty in ADEPT approaches, one of the most relevant was based on the design of multiplespacer systems..Closely related to ADEPT, new approaches to selectively deliver prodrug-releasing enzymes intumor cells have been still studied or proposed by means of gene (GDEPT), 作者: 凹處 時(shí)間: 2025-3-22 22:33
,Anthracycline–Formaldehyde Conjugates and Their Targeted Prodrugs,ehyde in vivo remains a?mystery. In vitro, doxorubicin reacts withformaldehyde to give firstly a?monomeric oxazolidine, doxazolidine, and secondly a?dimeric oxazolidine,doxoform. Doxorubicin reacts with formaldehyde in the presence of salicylamide to give the N-Mannich baseconjugate, doxsaliform. Do作者: 評(píng)論者 時(shí)間: 2025-3-23 03:06
Einführung in die Analyse von Prosatextening an enhanced therapeutic efficacy of theprodrugs compared to free doxorubicin in tumor models. Clinically, the (6-maleimidocaproyl)-hydrazonederivative of doxorubicin, which binds either to the monoclonal antibody BR96 or to endogenous albumin,has been evaluated in clinical trials.作者: AVID 時(shí)間: 2025-3-23 06:46 作者: acquisition 時(shí)間: 2025-3-23 10:12 作者: Fester 時(shí)間: 2025-3-23 15:39 作者: 不能逃避 時(shí)間: 2025-3-23 20:57 作者: Alveoli 時(shí)間: 2025-3-23 22:31
https://doi.org/10.1007/978-3-322-94758-1d via P450 CYP3A enzyme to an extremely cytotoxicderivative. Both nemorubicin and its metabolite have a?mechanism of action different from that ofdoxorubicin, with a?key role played by the nucleotide excision repair system. The drug is activelytested in clinics as a?single agent or in combination with cisplatin.作者: CHOP 時(shí)間: 2025-3-24 04:48 作者: FLIC 時(shí)間: 2025-3-24 10:01
Nemorubicin,d via P450 CYP3A enzyme to an extremely cytotoxicderivative. Both nemorubicin and its metabolite have a?mechanism of action different from that ofdoxorubicin, with a?key role played by the nucleotide excision repair system. The drug is activelytested in clinics as a?single agent or in combination with cisplatin.作者: 場(chǎng)所 時(shí)間: 2025-3-24 12:38 作者: monogamy 時(shí)間: 2025-3-24 17:49 作者: Between 時(shí)間: 2025-3-24 19:47 作者: finale 時(shí)間: 2025-3-25 01:43
Acid-Sensitive Prodrugs of Doxorubicin,for designing carrier-linked prodrugs with pH-dependentlinkers. In the past 20 years, a?spectrum of acid-sensitive doxorubicin prodrugs has been developedwith antibodies, serum proteins, and synthetic polymers. For a?number of these, a?convincingproof of concept has been obtained preclinically, show作者: Employee 時(shí)間: 2025-3-25 06:01
Doxorubicin Conjugates for Selective Delivery to Tumors, tumor site while releasing the cytotoxic drug..Among immuno-conjugates representing a?widely studied class of doxorubicin derivatives,the clinical development of cBR96-Dox, undoubtedly the most quintessential derivative, was discontinueddue to severe secondary effects. More potent cBR-96 analogues 作者: 表狀態(tài) 時(shí)間: 2025-3-25 11:10
,Anthracycline–Formaldehyde Conjugates and Their Targeted Prodrugs,raquinones, and as such are redox active. Their redoxchemistry leads to induction of oxidative stress and drug metabolites. An intermediate in reductive glycosidiccleavage is a?quinone methide, once proposed as an alkylating agent of DNA. Subsequent research nowimplicates formaldehyde as a?mediator 作者: Grating 時(shí)間: 2025-3-25 12:06 作者: incarcerate 時(shí)間: 2025-3-25 17:45
Nemorubicin,armitalia CarloErba Research Center in Italy. The idea was to develop doxorubicin analogues able to circumvent the emergenceof chemoresistance, in particular the multi-drug resistance. The drug was reported to be active in vitroagainst both murine and human tumor cells resistant to doxorubicin. Simi作者: Comprise 時(shí)間: 2025-3-25 22:24
Anthracycline Chemistry and Biology II978-3-540-75813-6Series ISSN 0340-1022 Series E-ISSN 1436-5049 作者: caldron 時(shí)間: 2025-3-26 02:07 作者: groggy 時(shí)間: 2025-3-26 06:38
Karsten KrohnSeries presents critical reviews of the present position and future trends in modern chemical research.Short and concise reports on chemistry, each written by the world renowned experts. Still valid a作者: 心胸狹窄 時(shí)間: 2025-3-26 08:43 作者: Simulate 時(shí)間: 2025-3-26 15:00 作者: Thyroxine 時(shí)間: 2025-3-26 17:08
978-3-642-09495-8Springer-Verlag Berlin Heidelberg 2008作者: Dictation 時(shí)間: 2025-3-26 21:42
https://doi.org/10.1007/978-3-476-99282-6ators have been developed. However, doxorubicin andclosely related anthracyclines still remain among the most effective antitumor agents. Multiple mechanismshave been proposed to explain their efficacy. They include inhibition of DNA-dependent functions, freeradical formation, and membrane interacti作者: 制定法律 時(shí)間: 2025-3-27 04:42 作者: hankering 時(shí)間: 2025-3-27 07:16 作者: 出沒(méi) 時(shí)間: 2025-3-27 11:31 作者: 障礙物 時(shí)間: 2025-3-27 15:24
Einführung in die Analyse von Prosatexten tumor site while releasing the cytotoxic drug..Among immuno-conjugates representing a?widely studied class of doxorubicin derivatives,the clinical development of cBR96-Dox, undoubtedly the most quintessential derivative, was discontinueddue to severe secondary effects. More potent cBR-96 analogues 作者: lethal 時(shí)間: 2025-3-27 20:56
https://doi.org/10.1007/978-3-476-98966-6raquinones, and as such are redox active. Their redoxchemistry leads to induction of oxidative stress and drug metabolites. An intermediate in reductive glycosidiccleavage is a?quinone methide, once proposed as an alkylating agent of DNA. Subsequent research nowimplicates formaldehyde as a?mediator 作者: 摻假 時(shí)間: 2025-3-28 01:04
https://doi.org/10.1007/978-3-476-98966-6-aminated sugar, namely 2-deoxy-.-rhamnose or 2-deoxy-.-fucose andthe second moiety is daunosamine, have been obtained upon synthesis of the appropriate activated sugarintermediate and glycosylation of the corresponding aglycones. The compounds containing 2-deoxy-.-fucose exhibit superior pharmacolo作者: Mammal 時(shí)間: 2025-3-28 06:01 作者: Fantasy 時(shí)間: 2025-3-28 07:16
10樓作者: 無(wú)王時(shí)期, 時(shí)間: 2025-3-28 14:14
10樓作者: PALMY 時(shí)間: 2025-3-28 14:36
10樓作者: 魯莽 時(shí)間: 2025-3-28 21:20
10樓
