標(biāo)題: Titlebook: Animal Models of Human Birth Defects; Aimin Liu Book 2020 Springer Nature Singapore Pte Ltd. 2020 Human birth defects.Animal model.Forward [打印本頁] 作者: 頌歌 時間: 2025-3-21 17:37
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書目名稱Animal Models of Human Birth Defects讀者反饋學(xué)科排名
作者: painkillers 時間: 2025-3-21 20:22
Book 2020rth defects and the essential role of animal models in shedding light on the underlying mechanisms of these disorders. Birth defects are the leading cause of infant deaths, and cost billions of dollars in care for those affected. Unfortunately, the lack of a clear understanding of the mechanisms lea作者: Hirsutism 時間: 2025-3-22 02:52 作者: faculty 時間: 2025-3-22 06:44
https://doi.org/10.1007/978-90-481-3138-9ions can be modeled using human pluripotent stem cells. At the core of understanding of these molecular processes are animal model studies that continue to be essential for elucidating the mechanisms underlying human pancreatic functions and diseases.作者: 相互影響 時間: 2025-3-22 12:31 作者: Dna262 時間: 2025-3-22 16:38
Animal Models of Pancreas Development, Developmental Disorders, and Disease,ions can be modeled using human pluripotent stem cells. At the core of understanding of these molecular processes are animal model studies that continue to be essential for elucidating the mechanisms underlying human pancreatic functions and diseases.作者: Glycogen 時間: 2025-3-22 17:03
What Do Animal Models Teach Us About Congenital Craniofacial Defects?,l bone, facial jaw bones, and two classes of diseases, ciliopathies and RASopathies. Studying the animal models of these rare diseases sheds light not only on the etiology and pathology of each disease, but also provides meaningful insights towards the mechanisms which regulate normal development of the head and face.作者: Sigmoidoscopy 時間: 2025-3-22 21:17 作者: BIPED 時間: 2025-3-23 01:52
Surya K. Mohanty,Debabrata Pandaas an excellent resource to identify the genetic bases of human kidney defects and have led to significantly improved diagnostics. Furthermore, genetic data from human CAKUT studies have also revealed novel genes regulating kidney differentiation.作者: innate 時間: 2025-3-23 06:52 作者: Ingratiate 時間: 2025-3-23 11:32
Vikram Dayal,Anantha Duraiappah,Nandan Nawnes of cardiac development and have been used to create cardiac disease models. In this chapter we examine the unique toolset available to zebrafish researchers and how those tools are used to interrogate the genetic and environmental contributions to CHDs.作者: 貧困 時間: 2025-3-23 14:52 作者: Inertia 時間: 2025-3-23 21:24
Mouse Models of Congenital Kidney Anomalies,as an excellent resource to identify the genetic bases of human kidney defects and have led to significantly improved diagnostics. Furthermore, genetic data from human CAKUT studies have also revealed novel genes regulating kidney differentiation.作者: 割公牛膨脹 時間: 2025-3-23 23:36
Animal Models for Understanding Human Skeletal Defects,pmental processes in laboratory animals will be a focus of discussion. This chapter will also highlight how current genome editing technologies can be applied to model various perturbations of human chromatin structure in laboratory animals.作者: 指令 時間: 2025-3-24 04:03
Using Zebrafish to Analyze the Genetic and Environmental Etiologies of Congenital Heart Defects,es of cardiac development and have been used to create cardiac disease models. In this chapter we examine the unique toolset available to zebrafish researchers and how those tools are used to interrogate the genetic and environmental contributions to CHDs.作者: 表兩個 時間: 2025-3-24 08:13
https://doi.org/10.1007/978-981-15-2389-2Human birth defects; Animal model; Forward and reverse genetics; Modelling diseases; Infectious disease作者: 蛛絲 時間: 2025-3-24 11:55
978-981-15-2391-5Springer Nature Singapore Pte Ltd. 2020作者: Density 時間: 2025-3-24 18:23
D. Michael Stoddart (Lecturer in Zoology)l birth defects. The appeal of mice for these experimental studies stems from the similarities between the physiology, anatomy, and reproduction of these small mammals with our own, but it is also based on a number of practical reasons: mice are easy to maintain in a laboratory environment, are incr作者: 驚惶 時間: 2025-3-24 19:19
Population processes in small mammals, as neurulation. Neural tube defects (NTDs) occur when neurulation fails and are among the most common structural birth defects in humans. The frequency of NTDs varies greatly anywhere from 0.5 to 10 in 1000 live births, depending on the genetic background of the population, as well as a variety of 作者: 打擊 時間: 2025-3-25 01:07
https://doi.org/10.1007/978-90-481-3138-9te blood sugar levels and enzyme secretion from the exocrine acinar cells to facilitate food digestion. These pancreatic functions are essential for life; therefore, preserving pancreatic function is of utmost importance. Pancreas dysfunction can arise either from developmental disorders or adult on作者: cruise 時間: 2025-3-25 03:49
The Landscape as a Human Agency,xtract key nutrients required to sustain our day-to-day functions. During development, it undergoes complex and highly specialized morphogenetic events to form functionally distinct organs. Its failure to develop properly leads to serious congenital diseases, which if left untreated are particularly作者: Pastry 時間: 2025-3-25 08:05 作者: 政府 時間: 2025-3-25 13:47 作者: antidepressant 時間: 2025-3-25 17:56
Vikram Dayal,Anantha Duraiappah,Nandan Nawnial for characterizing the molecular and cellular mechanisms that underlie these and other skeletal disorders. This chapter will explore the cellular origins of the vertebrate skeleton and introduce a selection of animal models for human disorders of the skull and facial bones, spinal column, and li作者: 指派 時間: 2025-3-25 23:53 作者: Harness 時間: 2025-3-26 01:27 作者: 涂掉 時間: 2025-3-26 05:29 作者: 星球的光亮度 時間: 2025-3-26 08:31
Aimin LiuIntroduces different animal models of human birth defects.Summarizes the current knowledge of a variety of common human birth defects.Discusses the essential roles of animal models in the effort to un作者: 閑逛 時間: 2025-3-26 15:43
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/a/image/157643.jpg作者: Free-Radical 時間: 2025-3-26 17:08 作者: TSH582 時間: 2025-3-26 21:19
D. Michael Stoddart (Lecturer in Zoology)for congenital birth malformations and human diseases. In this chapter, we will provide an overview of the methods, scientific advances, and serendipitous circumstances that have made these discoveries possible, with a special emphasis on how the use of genetics has propelled scientific progress in 作者: 悅耳 時間: 2025-3-27 01:25
The Landscape as a Human Agency,crotizing enterocolitis. Moreover, children often face complications from these surgical procedures, leading to secondary ailments. Consequently, a better understanding of gastrointestinal development is fundamental to the treatment and prevention of congenital GI maladies. This chapter will explore作者: 奇思怪想 時間: 2025-3-27 08:27 作者: Mammal 時間: 2025-3-27 12:40
A History of Mouse Genetics: From Fancy Mice to Mutations in Every Gene,for congenital birth malformations and human diseases. In this chapter, we will provide an overview of the methods, scientific advances, and serendipitous circumstances that have made these discoveries possible, with a special emphasis on how the use of genetics has propelled scientific progress in 作者: 河流 時間: 2025-3-27 17:00
Animal Models of Congenital Gastrointestinal Maladies,crotizing enterocolitis. Moreover, children often face complications from these surgical procedures, leading to secondary ailments. Consequently, a better understanding of gastrointestinal development is fundamental to the treatment and prevention of congenital GI maladies. This chapter will explore作者: 就職 時間: 2025-3-27 18:33
Animal Model Contributions to Congenital Metabolic Disease,tulate human disease as well as the need for multiple models of the same disease to fully investigate human disease aspects. Finally, we highlight research on the GM2 gangliosidoses Tay-Sachs and Sandhoff disease to illustrate the important role of both engineered traditional laboratory animal model作者: 敬禮 時間: 2025-3-27 21:55
A History of Mouse Genetics: From Fancy Mice to Mutations in Every Gene,l birth defects. The appeal of mice for these experimental studies stems from the similarities between the physiology, anatomy, and reproduction of these small mammals with our own, but it is also based on a number of practical reasons: mice are easy to maintain in a laboratory environment, are incr作者: anniversary 時間: 2025-3-28 05:59 作者: 表否定 時間: 2025-3-28 07:38
Animal Models of Pancreas Development, Developmental Disorders, and Disease,te blood sugar levels and enzyme secretion from the exocrine acinar cells to facilitate food digestion. These pancreatic functions are essential for life; therefore, preserving pancreatic function is of utmost importance. Pancreas dysfunction can arise either from developmental disorders or adult on作者: 藐視 時間: 2025-3-28 13:46
Animal Models of Congenital Gastrointestinal Maladies,xtract key nutrients required to sustain our day-to-day functions. During development, it undergoes complex and highly specialized morphogenetic events to form functionally distinct organs. Its failure to develop properly leads to serious congenital diseases, which if left untreated are particularly作者: 乞丐 時間: 2025-3-28 16:50
Mouse Models of Congenital Kidney Anomalies,. CAKUT covers a wide range of malformations that derive from deficiencies in embryonic kidney and lower urinary tract development, including renal aplasia, hypodysplasia, hypoplasia, ectopia, and different forms of ureter abnormalities. The majority of the genetic causes of CAKUT remain unknown. Re作者: Instinctive 時間: 2025-3-28 19:04 作者: 輪流 時間: 2025-3-29 02:08
Animal Models for Understanding Human Skeletal Defects,ial for characterizing the molecular and cellular mechanisms that underlie these and other skeletal disorders. This chapter will explore the cellular origins of the vertebrate skeleton and introduce a selection of animal models for human disorders of the skull and facial bones, spinal column, and li作者: LAVA 時間: 2025-3-29 05:48 作者: reperfusion 時間: 2025-3-29 08:50
