標(biāo)題: Titlebook: Alpha-1 Antitrypsin; Role in Health and D Adam Wanner,Robert A. Sandhaus Book 2016 Springer International Publishing Switzerland 2016 Genet [打印本頁] 作者: Carter 時間: 2025-3-21 18:17
書目名稱Alpha-1 Antitrypsin影響因子(影響力)
書目名稱Alpha-1 Antitrypsin影響因子(影響力)學(xué)科排名
書目名稱Alpha-1 Antitrypsin網(wǎng)絡(luò)公開度
書目名稱Alpha-1 Antitrypsin網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Alpha-1 Antitrypsin被引頻次
書目名稱Alpha-1 Antitrypsin被引頻次學(xué)科排名
書目名稱Alpha-1 Antitrypsin年度引用
書目名稱Alpha-1 Antitrypsin年度引用學(xué)科排名
書目名稱Alpha-1 Antitrypsin讀者反饋
書目名稱Alpha-1 Antitrypsin讀者反饋學(xué)科排名
作者: 推遲 時間: 2025-3-21 22:32 作者: 柏樹 時間: 2025-3-22 02:46 作者: JOT 時間: 2025-3-22 06:53
Jaroslav Smítal,Marta ?tefánkovápe associated with severe alpha-1 antitrypsin deficiency in North America. This percentage corresponds to a 48-fold increase in the detection rate when compared to its estimated prevalence in the general population. The age at the time of testing was 57.3?±?15 years in the overall population and 51.作者: fertilizer 時間: 2025-3-22 12:46
Ashwini Jadhav,Sankunny Mohan Karuppayillmonary disease (COPD) (Campos et al., Chest 128(3):1179–86, 2005). The importance of diagnosing AATD-related lung disease is centered around family genetic counseling and the availability of specific therapy.作者: 過于平凡 時間: 2025-3-22 16:45 作者: 入伍儀式 時間: 2025-3-22 17:21 作者: PALL 時間: 2025-3-22 22:08 作者: 冒失 時間: 2025-3-23 04:18 作者: Jacket 時間: 2025-3-23 08:00
United States Targeted Detection Program for Alpha-1 Antitrypsin Deficiency,pe associated with severe alpha-1 antitrypsin deficiency in North America. This percentage corresponds to a 48-fold increase in the detection rate when compared to its estimated prevalence in the general population. The age at the time of testing was 57.3?±?15 years in the overall population and 51.作者: 尋找 時間: 2025-3-23 13:34 作者: Stress-Fracture 時間: 2025-3-23 16:06 作者: locus-ceruleus 時間: 2025-3-23 21:51
2197-7372 e organizations in the treatment of these diseases. Written for pulmonary clinicians and scientists, .Alpha-1 Antitrypsin: Role in Health and Disease .is a valuable resource that sheds light on this rare disease..978-3-319-79484-6978-3-319-23449-6Series ISSN 2197-7372 Series E-ISSN 2197-7380 作者: 打包 時間: 2025-3-23 23:50 作者: Myofibrils 時間: 2025-3-24 04:53 作者: 可耕種 時間: 2025-3-24 08:36
Alpha-1 Antitrypsin978-3-319-23449-6Series ISSN 2197-7372 Series E-ISSN 2197-7380 作者: 現(xiàn)暈光 時間: 2025-3-24 14:37 作者: 純樸 時間: 2025-3-24 15:16 作者: V切開 時間: 2025-3-24 23:03 作者: Wordlist 時間: 2025-3-25 01:37 作者: 粗魯?shù)娜?nbsp; 時間: 2025-3-25 04:26
Jaroslav Smítal,Marta ?tefánková barrier to lifestyle modifications, genetic counseling, and specific treatment. Targeted screening allows for high detection rates and lower costs than population screening. Little is known about the prevalence and demographic and clinical characteristics of individuals with the main AATD genotypes作者: AMOR 時間: 2025-3-25 08:08
Ashwini Jadhav,Sankunny Mohan Karuppayil emphysema and/or bronchiectasis (Silverman and Sandhaus, N Engl J Med 360(26):2749–57, 2009). It also represents the most common reason that an adult is tested for AATD (The Alpha 1-Antitrypsin Deficiency Registry Study Group, Chest 106(4):1223–32, 1994). This bias toward testing individuals with l作者: SEEK 時間: 2025-3-25 14:35 作者: 秘密會議 時間: 2025-3-25 17:43 作者: 抗原 時間: 2025-3-25 21:40 作者: Agnosia 時間: 2025-3-26 01:19 作者: figure 時間: 2025-3-26 08:08 作者: 珊瑚 時間: 2025-3-26 10:36
Alpha-1-Antitrypsin and the Serpins,ease can result in both loss-of-function and gain-of-function disabilities. In biology, α-1-antitrypsin is the archetype of an extensive superfamily of serine proteinase inhibitors, the serpins, which control essential intra- and extracellular functions. A central feature of the serpins is their ext作者: 聰明 時間: 2025-3-26 12:51 作者: Obvious 時間: 2025-3-26 20:27
Misfolding and Polymerisation of Alpha1-Antitrypsin: Conformational Pathology and Therapeutic Targe such as the common Z (Glu342Lys) variant vulnerable to misfolding and polymerisation that underlie the disease mechanisms of α1 -antitrypsin deficiency. Combinations of gain- and loss-of-function effects explain the observed disease behaviour. Detailed studies of these processes lead to hypotheses 作者: endure 時間: 2025-3-26 21:58
Managing the Adaptive Proteostatic Landscape: Restoring Resilience in Alpha-1 Antitrypsin Deficiencially recognized and managed by a sophisticated network mainly composed of folding chaperones (the chaperome) and degradative (ubiquitin and autophagy–lysosome based) components referred to as proteostasis. The .roteostasis .etwork (PN) defines different .uinary states (Q-states) for each protein in作者: ineptitude 時間: 2025-3-27 04:39
United States Targeted Detection Program for Alpha-1 Antitrypsin Deficiency, barrier to lifestyle modifications, genetic counseling, and specific treatment. Targeted screening allows for high detection rates and lower costs than population screening. Little is known about the prevalence and demographic and clinical characteristics of individuals with the main AATD genotypes作者: 畢業(yè)典禮 時間: 2025-3-27 08:49
Lung Disease of Alpha-1 Antitrypsin Deficiency, emphysema and/or bronchiectasis (Silverman and Sandhaus, N Engl J Med 360(26):2749–57, 2009). It also represents the most common reason that an adult is tested for AATD (The Alpha 1-Antitrypsin Deficiency Registry Study Group, Chest 106(4):1223–32, 1994). This bias toward testing individuals with l作者: 通情達(dá)理 時間: 2025-3-27 13:05 作者: Mets552 時間: 2025-3-27 14:12 作者: cylinder 時間: 2025-3-27 20:41
The Alpha-1 Constellation of Voluntary Health Organizations as a Paradigm for Confronting Rare Disen diseases. Rare disease patients and the clinicians and researchers who serve them lack the benefits of a large patient cohort for studies, federally funded trials and testing, public awareness, and market-driven pharmaceutical and other therapeutic initiatives. They must rely more heavily on a sma作者: Hyperplasia 時間: 2025-3-27 22:19
Book 2016sease in adults and children and is associated with chronic obstructive lung disease in adults. While it is a rare condition, the mechanisms underlying the clinical manifestations of this deficiency have been largely clarified. Treatment, however, is?available only for the lung disease that arises f作者: Prostatism 時間: 2025-3-28 05:59 作者: CORD 時間: 2025-3-28 09:43 作者: 記憶法 時間: 2025-3-28 12:39
https://doi.org/10.1007/978-94-009-8105-8 misfolded ATZ, particularly the autophagic pathway, are believed to play a critical role, and FDA-approved drugs that enhance autophagy and can be repurposed appear to be attractive candidates for treatment. Several other promising drug-, cell-, or gene-based therapeutic strategies are being developed for this liver disease.作者: Nonporous 時間: 2025-3-28 15:12
https://doi.org/10.1007/978-94-009-8105-8c fibrosis, and alpha-1 antitrypsin-replete chronic obstructive pulmonary disease among others. While the results of pivotal clinical trials have not been reported to date, new indications for alpha-1 antitrypsin therapy are likely to emerge in the future based on currently available scientific data.作者: 全神貫注于 時間: 2025-3-28 19:04 作者: Adulate 時間: 2025-3-29 00:17
