作者: packet 時間: 2025-3-21 20:40
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/a/image/152327.jpg作者: 接合 時間: 2025-3-22 03:03
Aldehyde Dehydrogenases978-981-13-6260-6Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: 捐助 時間: 2025-3-22 07:25 作者: farewell 時間: 2025-3-22 10:40 作者: triptans 時間: 2025-3-22 15:55 作者: Circumscribe 時間: 2025-3-22 18:26
978-981-13-6262-0Springer Nature Singapore Pte Ltd. 2019作者: inhibit 時間: 2025-3-22 21:39 作者: SUGAR 時間: 2025-3-23 03:17 作者: arousal 時間: 2025-3-23 09:25 作者: 責任 時間: 2025-3-23 10:42 作者: Infusion 時間: 2025-3-23 16:47
https://doi.org/10.1007/978-0-387-21528-0igue, pulmonary crackles, and peripheral edema. Being a terminal phase of most myocardial lesions, HF has become a leading cause of mobility and mortality worldwide, associated with heavy clinical burden and economic costs affecting over 23 million people [14]. There is an increase to 5.5% with syst作者: VOC 時間: 2025-3-23 21:54 作者: 針葉類的樹 時間: 2025-3-23 23:12
https://doi.org/10.1007/978-94-017-1209-5lent myocardial ischemia, and sudden death. The prevalence of coronary spasm is higher among East Asians probably due to genetic as well as environmental factors. ALDH2 eliminates toxic aldehydes including 4-hydroxy-2-nonenal (4-HNE) derived from lipid peroxidation and acrolein in tobacco smoking as作者: ADOPT 時間: 2025-3-24 03:20 作者: ventilate 時間: 2025-3-24 07:28
A Digital Twin Platform for Industrie 4.0s 4-hydroxynonenal (4HNE). Aldehyde dehydrogenase (ALDH) 2 is a mitochondrial enzyme that has been found to detoxify these deleterious aldehydes and thereby mitigate cardiac damage. Furthermore, its protective role in cellular signaling reverses aberrations caused by hyperglycemia, thereby protectin作者: 貿(mào)易 時間: 2025-3-24 12:52
Edward Curry,Simon Scerri,Tuomo Tuikkach imposes global health burden. Sepsis-induced organ dysfunction, including circulatory and cardiac dysfunction, hepatic dysfunction, renal dysfunction, etc., contributes to high mortality and long-term disability of sepsis patients. Altered inflammatory response, ROS and reactive aldehyde stress, 作者: Aggressive 時間: 2025-3-24 15:39
Edward Curry,Simon Scerri,Tuomo Tuikka effect of genetic susceptibility and numerous vascular risk factors, including hypertension, diabetes, excessive alcohol intake, obesity, and dyslipidemia. Mitochondrial aldehyde dehydrogenase (ALDH2) is a vital enzyme metabolizing various acetaldehyde and toxic aldehydes. The ALDH2 enzymatic activ作者: HPA533 時間: 2025-3-24 19:05 作者: Ostrich 時間: 2025-3-25 02:26 作者: 開花期女 時間: 2025-3-25 05:13 作者: 危機 時間: 2025-3-25 08:31
Social Locality in Data Storage,s have been proposed for the biology of aging including free radical accumulation, DNA damage, apoptosis, telomere shortening, autophagy failure, and disturbed autonomic response. Aging is also closely associated with progressive deterioration of cardiovascular and neurological functions. Linkage, g作者: 貧窮地活 時間: 2025-3-25 14:26 作者: AIL 時間: 2025-3-25 18:18 作者: 懶惰民族 時間: 2025-3-25 23:07
The Bidirectional Effect of Defective , Polymorphism and Disease Prevention,se effects on physiological indices, such as blood pressure, body mass index, levels of lipids, and hepatic deviation enzymes in the blood, than in non-. carriers. Therefore, opportunities to reconsider their excessive drinking habit before adverse events occur can be missed. To perform effective di作者: Meditative 時間: 2025-3-26 01:46 作者: 全國性 時間: 2025-3-26 06:13 作者: 同來核對 時間: 2025-3-26 11:28 作者: 收集 時間: 2025-3-26 15:55
Yuan Zhang,Chunxiang Xu,Xuemin Sherman Shen to the adverse cardiac effects of similar amounts of alcohol. To understand this discrepancy, we discuss the autonomic and cardiac effects of alcohol and its metabolite acetaldehyde in a model of hypertension, the spontaneously hypertensive rat (SHR) and female rats. We present evidence that enhanc作者: Chromatic 時間: 2025-3-26 20:44 作者: Congruous 時間: 2025-3-26 22:03
https://doi.org/10.1007/978-0-387-21528-0se effects on physiological indices, such as blood pressure, body mass index, levels of lipids, and hepatic deviation enzymes in the blood, than in non-. carriers. Therefore, opportunities to reconsider their excessive drinking habit before adverse events occur can be missed. To perform effective di作者: Ischemic-Stroke 時間: 2025-3-27 02:14
Edward Curry,Simon Scerri,Tuomo Tuikkaondria to detoxify aldehydes, in septic organ dysfunction. In this article, we will review the presentations and pathophysiology of septic organ dysfunction, as well as summarize and discuss the recent insights regarding ALDH2 in sepsis.作者: mechanical 時間: 2025-3-27 05:18
Edward Curry,Simon Scerri,Tuomo Tuikkating ALDH2 may represent a promising avenue for protection against stroke injury. This review will mainly focus on clinical and epidemiological evidence and the underlying molecular mechanisms involved in the protective effect of ALDH2 in stroke-related injury.作者: mighty 時間: 2025-3-27 09:49
Social Locality in Data Storage,med an important enzyme for detoxification of reactive aldehydes. Here, we will briefly review the tie between ALDH2 and cardiovascular aging process. While recent work on ALDH2 research has broadened the pathogenic mechanisms of ALDH2 mutation or deficiency, therapeutic potential targeting ALDH2 in作者: Lignans 時間: 2025-3-27 14:31
0065-2598 mpanies developing new tools for cardiometabolic and chronic diseases treatment will also find this a valuable resource.. .978-981-13-6262-0978-981-13-6260-6Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: ILEUM 時間: 2025-3-27 21:25 作者: infarct 時間: 2025-3-27 22:41
Edward Curry,Simon Scerri,Tuomo Tuikkaeen ALDH2 and atherosclerosis, which provided insights on targeting ALDH2 for therapeutic intervention of atherosclerosis. In this review, these inspiring studies will be discussed, and the clinical implications and concerns will be expounded.作者: 立即 時間: 2025-3-28 03:11
Edward Curry,Simon Scerri,Tuomo Tuikkat in approximately 560 million East Asians. ALDH2*2 demonstrates its effect on alcohol consumption limiting and alcoholism developing protection, and this variant is recently found to have an important impact on human health. This chapter focuses on its potential effect on cancer therapy, especially for chemotherapeutics with anthracyclines.作者: ANT 時間: 2025-3-28 10:10 作者: 注入 時間: 2025-3-28 14:27 作者: defray 時間: 2025-3-28 16:13
https://doi.org/10.1007/978-94-017-1209-5st Asians and is a significant risk factor for both coronary spasm and AMI through accumulation of toxic aldehydes, thereby contributing to oxidative stress, endothelial damage, vasoconstriction, and thrombosis. Toxic aldehydes are thus identified as risk factors to be targeted for the treatment of coronary spasm and AMI.作者: Fermentation 時間: 2025-3-28 19:06
Association of East Asian Variant Aldehyde Dehydrogenase 2 Genotype (,2*2*) with Coronary Spasm andst Asians and is a significant risk factor for both coronary spasm and AMI through accumulation of toxic aldehydes, thereby contributing to oxidative stress, endothelial damage, vasoconstriction, and thrombosis. Toxic aldehydes are thus identified as risk factors to be targeted for the treatment of coronary spasm and AMI.作者: aphasia 時間: 2025-3-28 23:32 作者: 悅耳 時間: 2025-3-29 03:55
Aldehyde Dehydrogenase (ALDH) 2 in Diabetic Heart Diseases,g cardiac function. This chapter assesses the role of ALDH2 in diabetic heart diseases by examining preclinical studies where ALDH2 activity is perturbed in both decreased and increased directions. In doing so, issues in improving ALDH2 activity in select human populations are elucidated, and further research directions are discussed.作者: 約會 時間: 2025-3-29 10:27
ALDH2 Polymorphism and Ethanol Consumption: A Genetic-Environmental Interaction in Carcinogenesis, when ALDH2 mutation combined with heavy alcohol consumption, suggesting a genetic-environmental interaction in carcinogenesis. This may provide us with a potential target for cancer prevention and treatment.作者: 安定 時間: 2025-3-29 14:23
Book 2019ese processes. It thoroughly reviews the roles of ALDH family in alcohol metabolism, as well as recent findings of their emerging roles in a variety of human pathologies such as cardiovascular diseases, diabetes, obesity, stroke, cancer, liver diseases and kidney diseases. Delicate contribution of A作者: 懲罰 時間: 2025-3-29 16:45 作者: 嘮叨 時間: 2025-3-29 21:45 作者: BULLY 時間: 2025-3-30 03:39 作者: 荒唐 時間: 2025-3-30 04:20
Aldehyde Dehydrogenases Genetic Polymorphism and Obesity: From Genomics to Behavior and Health,nsumption behavior in physiological mechanism studies, we proposed a model by which the physiological and behavioral consequences of alcohol consumption serve as an intermediary process between polymorphisms in . and obesity.作者: SHRIK 時間: 2025-3-30 10:59 作者: Observe 時間: 2025-3-30 14:20
https://doi.org/10.1007/978-0-387-21528-0olic dysfunction and an increase to 36.0% with diastolic dysfunction in people 60?years or older [85]. The costs accompanied with heart failure stand 2–3% of the total healthcare system expenditure in high-income countries and are expected to increase >2-fold in the next 2 decades [34].
